CDK5 opens the way for DLC1
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چکیده
منابع مشابه
CDK5 opens the way for DLC1
Macrophages show neutrophils the exit T auzin et al. describe how macrophages resolve infl ammation by inducing neutrophils to leave wounded tissue. Zebrafi sh neutrophils are attracted to wounds by reactive oxygen species (ROS) that activate the Src family kinase Lyn. Neutrophil-mediated infl ammation is partly resolved by apoptosis and the cells' subsequent engulfment by macrophages. But neut...
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DLC1 is a tumor suppressor protein whose full activity depends on its presence at focal adhesions, its Rho-GTPase activating protein (Rho-GAP) function, and its ability to bind several ligands, including tensin and talin. However, the mechanisms that regulate and coordinate these activities remain poorly understood. Here we identify CDK5, a predominantly cytoplasmic serine/threonine kinase, as ...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2014
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.2075iti2